Evidence Based Resources on Gender Medicine

There has been a significant amount of research into, and media coverage of, “gender affirming care” over the last number of years. However, it has been hard to find legacy media coverage that has provided any balance. Meanwhile, the academic papers promoted by activists tend to frequently have a weak evidence base. On this page, FDNHSA provides links to trusted and evidence-based resources that highlight some of the key issues surrounding the promotion of “gender affirming care.”

These resources include systematic reviews, academic papers and articles from the independent media, as well as video presentations and documentaries.

Evidence Reviews and Policy Changes

England: The CASS Review

England. CASS Review. Independent review of gender identity services for children and young people: Final report.

England. Peer reviewed systematic reviews commissioned to inform the work of the CASS Review are all available open access here.

England. National Institute for Health and Care Excellence (2020). Evidence review: Gonadotrophin releasing hormone analogues for children and adolescents with gender dysphoria.

England. National Institute for Health and Care Excellence (2020). Evidence review: Gender-affirming hormones for children and adolescents with gender dysphoria.

Other International Reviews

Sweden: A systematic review of hormone treatment for children with
gender dysphoria and recommendations for research.

Finland: Recommendation of the Council for Choices in Health Care in Finland (COHERE Finland) Medical treatment procedures for dysphoria related to minors’ gender variances.

Germany: Beyond NICE: Updated systematic review on the current evidence for using puberty blockers and cross-sex hormones in minors with gender dysphoria.

The Myth of “Reliable Research” in Pediatric Gender Medicine: A critical evaluation of the Dutch Studies—and research that has followed.

Critiques of Gender Affirming Care and the Transgender Phenomenon

Australian Doctors Federation. Gender Dysphoria in Children, featuring Helen Joyce, Jillian Spencer, Andrew Amos & John Whitehall.

Desexing Society EP08 – What Next?

Trans Madness: The Way Out.

‘Gender-Affirming Care Is Dangerous. I Know Because I Helped Pioneer It.’

Managing Gender Dysphoria in Children. A Need for Caution.

The Times View on Treating Gender with Drugs: Quack Medicine.

Australian Psychiatrist: concerns re: the affirmation model for children with gender dysphoria. (Video)

The trans fad. A new study has shown that most gender-confused kids grow out of it.

Transgender Research: Five Things Every Parent and Policy-Maker Should Know.

Youth Gender Transition Is Pushed Without Evidence. Psychotherapy, not hormones and surgery, is increasingly the first line of treatment abroad.

Science, the Transgender Phenomenon, and the Young | Abigail Shrier. (Video)

The New Epidemiological Trend: Acute Adolescent Onset in Females

Gender Dysphoria and Anorexia in Adolescent Females. Significant parallels between gender dysphoria and anorexia in teen girls calls for a nuanced and developmentally-informed approach.

A New Flight from Womanhood? The Importance of Working Through Experiences Related to Exposure to Pornographic Content in Girls Affected by Gender Dysphoria.

Informed Consent

Informed consent and childhood gender dysphoria: emerging complexities in diagnosis and treatment.

Reconsidering Informed Consent for Trans-Identified Children, Adolescents, and Young Adults.

Puberty Blockers

The impact of suppressing puberty on neuropsychological function: A review.

The Effect of Puberty Blockers on the Teenage Brain | Sallie Baxendale. (Video)

Desistance, Detransition and Regret

As Kids, They Thought They Were Trans. They No Longer Do.

Iatrogenic Harm in Gender Medicine.

The Detransition Rate Is Unknown.

Transition Regret and Detransition: Meanings and Uncertainties.

The Wounds That Won’t Heal | Detransitioner Chloe Cole (Video)

The Detransition Diaries: Saving Our Sisters. (Video)

DETRANS: The Dangers of Gender-Affirming Care. (Video)

The Lost Boys: Searching for Manhood. (Video)

Suicide Narrative

All-cause and suicide mortalities among adolescents and young adults who contacted specialised gender identity services in Finland in 1996–2019: a register study.

On Suicide Rates in children and adolescents with gender dysphoria.

The Distortions in Jack Turban’s Psychology Today Article on ‘Gender Affirming Care’. Turban’s public statements on pediatric gender medicine have been less than honest.

The WPath Files

The WPATH Files. PSEUDOSCIENTIFIC SURGICAL AND HORMONAL
EXPERIMENTS ON CHILDREN, ADOLESCENTS, AND VULNERABLE ADULTS.

The WPATH Files: ‘One of the Biggest Medical Scandals of the Century’ | Free Speech Nation. (Video)

Alternative Approaches

A Clinical Guide for Therapists Working with Gender-Questioning Youth.

Gender Toolkit

Psychodynamic psychotherapy for gender dysphoria is not conversion therapy.

Testosterone in Women & Girls

Pelvic Floor Dysfunction in Transgender Men on Gender-affirming Hormone Therapy: A Descriptive Cross-sectional Study.